| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6269515 | Journal of Neuroscience Methods | 2012 | 11 Pages |
We present a comprehensive methodology for identifying cerebral areas involved in event-related changes of electromagnetic activity of the human brain, and also for tracing the temporal evolution of this activity. Information from pre- and peristimulus time intervals - in terms of event-related synchronization (ERS) and desynchronization (ERD) of the magnetoencephalographic (MEG) signal - was directly incorporated in the relevant test statistics. For the individual steps of the analysis, we used particular estimations of the time-frequency distribution of the energy along with particular error control methods, that is, short-time Fourier transform and false-discovery rate at the sensor level and multitapers and familywise error rate at the source level. This procedure was applied to two types of group-level tests, a within-condition test and a between-conditions test. The performance of the proposed methodology is assessed by (1) analyzing the event-related brain activity from two experimental conditions of an auditory MEG experiment-passive listening to a sequence of frequency-modulated sweeps and their active categorization with respect to the direction of frequency modulation, and (2) comparing the findings with those obtained with a widely used cluster-based analysis.
⺠Identification and localization of sources of oscillatory activity in the brain. ⺠Group-level statistical tests: a within- and a between-conditions test. ⺠Localization of MEG desynchronization in an auditory experiment. ⺠Temporal evolution of beta band induced activity across the brain.
