Article ID Journal Published Year Pages File Type
6269517 Journal of Neuroscience Methods 2012 10 Pages PDF
Abstract
► Biaxial stretch injury model applied to SHSY-5Y cells cultured on silicone substrate. ► Precisely characterized strain and strain rates with high speed imaging system. ► Identified three injury regimes in stretch-induced dose-response curves of cells. ► Sharp decline from live to dead is noted in a narrow range of strain (30-55%). ► Our in vitro model is useful in precise evaluation of injury criterion (risk) curves.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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