Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6269595 | Journal of Neuroscience Methods | 2011 | 11 Pages |
Abstract
⺠We demonstrate how current histological methods for examining CNS implanted devices are lacking. ⺠We describe a method to consistently capture CNS microdevices within an intact tissue section. ⺠A protocol and discussion on labeling and imaging these thicker tissue slices are presented. ⺠Microscopy data from along the length of in situ CNS microdevices are shown and quantified. ⺠Results include multi-nucleated responses at device interfaces, and myelin reorganization.
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Neuroscience
Neuroscience (General)
Authors
Andrew J. Woolley, Himanshi A. Desai, Mitchell A. Steckbeck, Neil K. Patel, Kevin J. Otto,