| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6269744 | Journal of Neuroscience Methods | 2011 | 8 Pages |
Abstract
⺠Assessing functional integration of grafts in models of cell based therapies is essential. ⺠We validated M4-BAC-GFP mice as tissue donor in a model of Huntington's disease. ⺠The embryonic striatal tissue survived, integrated, continued to express GFP up to 6 months. ⺠BAC-GFP mice provide a novel way to study graft-host interaction in neurodegenerative models.
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Authors
Máté Döbrössy, Alexander Klein, Nari Janghra, Guido Nikkhah, Stephen B. Dunnett,