Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6269949 | Journal of Neuroscience Methods | 2010 | 9 Pages |
Abstract
ⶠMice deleted for snca are efficient hosts for producing anti-α-synuclein antibodies. ⶠIgG AS11 recognizes the N-terminus of human α-synuclein. ⶠAS11 detects intraneuronal inclusions containing aggregated α-synuclein. ⶠAS11 stains pathological glial cytoplasmic inclusions in brains of patients with MSA. ⶠAS11 detects pathological forms of α-synuclein in Lewy bodies in patients with PD.
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Authors
Anne-Laure J. Mougenot, Dominique Bétemps, Kevin N. Hogeveen, Gabor G. Kovacs, Latifa Chouaf-Lakhdar, Ollivier Milhavet, Sylvain Lehmann, Stéphane Legastelois, Jean-Jacques Pin, Thierry G. Baron,