Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6271911 | Neuroscience | 2015 | 13 Pages |
Abstract
PACAP6-38, M65 and VIP6-28, which were described as antagonists in numerous studies in several model systems, act as agonists on TRG primary sensory neurons. Currently unknown receptors or splice variants linked to distinct signal transduction pathways might explain these differences.
Keywords
D-MEMGTPCPMGTPγSGPCRsCGRPcAMPDMSOECsG protein-coupled receptors[Ca2+]icyclic adenosine 3′,5′-monophosphateadenylate cyclaseChoGDPdiacylglycerolDimethyl sulfoxideextracellular solutionDAGcount per minuteintracellular free calcium concentrationcalcitonin gene-related peptideChinese Hamster Ovary cell line
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Authors
Ã. Sághy, M. Payrits, Zs. Helyes, D. ReglÅdi, E. Bánki, G. Tóth, A. Couvineau, Ã. SzÅke,