| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6272021 | Neuroscience | 2015 | 9 Pages |
Abstract
In this study, we have demonstrated that LXA4 potently alleviate radicular pain in a rat model of non-compressive lumbar disc herniation. The anti-inflammatory and pro-resolution properties of LXA4 have shown a great promise for the management of radicular pain caused by intervertebral disc herniation.
Keywords
LXA4CCDDRGERKJnkTGF-β1PBSPWTCCIdorsal root ganglionc-Jun N-terminal kinaseMAPKchronic constrictive injuryinflammationinterleukinTransforming growth factor-β1analysis of varianceANOVAEnzyme-linked immunosorbent assayELISAtumor necrosis factor-αRadicular painSpinal cordTNF-αIntervertebral disc herniationlipoxin A4Phosphate-buffered salineRatNucleus pulposuspolymerase chain reactionPCRmitogen-activated protein kinaseextracellular signal-regulated kinase
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Authors
G.-S Miao, Z.-H Liu, S.-X Wei, J.-G Luo, Z.-J Fu, T. Sun,