| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6272902 | Neuroscience | 2015 | 14 Pages |
Abstract
These results show selective behavioral changes in BDNF HET rats, at baseline or after chronic CORT treatment and add to our understanding of the role of BDNF and its interaction with stress. Importantly, this study demonstrates the utility of the BDNF HET rat in investigations into the pathophysiology of various psychiatric disorders.
Keywords
PFCTrkBN-methyl-d-aspartateNMDABDNFHETPosttraumatic stress disorderPTSDSchizophreniaanalysis of varianceANOVACognitionBrain-derived neurotrophic factorprefrontal cortexunconditioned stimulusconditioning stimulusHypothalamic–pituitary axisHPAwildtypeheterozygoustropomyosin-related kinase BCORTCorticosteroneMineralocorticoid receptorglucocorticoid receptor
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Authors
A. Gururajan, R.A. Hill, M. van den Buuse,