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Dimethyl fumarate attenuates 6-OHDA-induced neurotoxicity in SH-SY5Y cells and in animal model of Parkinson's disease by enhancing Nrf2 activity

Article ID Journal Published Year Pages File Type
6273103 Neuroscience 2015 32 Pages PDF
Keywords
6-HydroxydopamineNAD(P)H:quinine oxidoreductase 1GCLMGCLCNQO-1Heme oxygenase-1DOPACHO-1GSHNrf2GFAPDMF6-OHDAJnk3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromidekeap1c-Jun N-terminal kinaseHPLC–MS/MSMTTImmunohistochemistryIHCAlzheimer’s diseaseDopaminedimethyl fumaratedihydroxyphenylacetic acidHigh-performance liquid chromatography–tandem mass spectrometryantioxidant response elementslactate dehydrogenaseLDHMultiple sclerosisAREhomovanillic acidGlial fibrillary acidic proteinKelch-like ECH-associated protein 1HVAGlutathione
Related Topics
Life Sciences Neuroscience Neuroscience (General)
Preview
Dimethyl fumarate attenuates 6-OHDA-induced neurotoxicity in SH-SY5Y cells and in animal model of Parkinson's disease by enhancing Nrf2 activity
Authors
X. Jing, H. Shi, C. Zhang, M. Ren, M. Han, X. Wei, X. Zhang, H. Lou,
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Journal
Neuroscience
Journal: Neuroscience
Related Categories
6-Hydroxydopamine
NAD(P)H:quinine oxidoreductase 1
GCLM
GCLC
NQO-1
Heme oxygenase-1
DOPAC
HO-1
GSH
Nrf2
GFAP
DMF
6-OHDA
Jnk
3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide
keap1
c-Jun N-terminal kinase
HPLC–MS/MS
MTT
Immunohistochemistry
IHC
Alzheimer’s disease
Dopamine
dimethyl fumarate
dihydroxyphenylacetic acid
High-performance liquid chromatography–tandem mass spectrometry
antioxidant response elements
lactate dehydrogenase
LDH
Multiple sclerosis
ARE
homovanillic acid
Glial fibrillary acidic protein
Kelch-like ECH-associated protein 1
HVA
Glutathione
Behavioral Neuroscience
Biological Psychiatry
Cellular and Molecular Neuroscience
Cognitive Neuroscience
Developmental Neuroscience
Endocrine and Autonomic Systems
Neurology
Neuroscience (General)
Sensory Systems
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