Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6273372 | Neuroscience | 2014 | 12 Pages |
Abstract
- β-Caryophyllene (BCP) prevented astrocytes from glutamate-induced cytotoxicity.
- BCP inhibits ROS production and mitochondrial dysfunction.
- BCP upregulates the glutathione antioxidant system through the Nrf2 pathway.
- Antioxidant effects of BCP are dependent of CB2R activation.
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Authors
L.C. Assis, M.R. Straliotto, D. Engel, M.A. Hort, R.C. Dutra, A.F. de Bem,