Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6274324 | Neuroscience | 2013 | 7 Pages |
Abstract
GlyT2 inhibition induced glycinergic tonic currents, which might be the underlying mechanism for the observed suppression of spontaneous action potential activity by ALX 1393 in the spinal ventral horn. Silencing neuronal action potential activity by blocking GlyT2 might be a novel principle to inhibit locomotor circuits in the ventral horn area and to induce muscle relaxation.
Keywords
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
V.-S. Eckle, B. Antkowiak,