| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6274527 | Neuroscience | 2013 | 12 Pages |
Abstract
The behavioral and electrophysiological observations described in this report demonstrate that PAT mediates, at least partially, its anti-inflammatory action by potentiating the α7-nAChR. These results indicate that PAT has a potential for new therapeutic applications as anti-inflammatory and analgesic agent.
Keywords
Nicotinic receptor antagonistsintracerebroventricularICVMBSNGFMLAα7-nicotinic acetylcholine receptorHEPESPWDα7-nAChRAChAcetylcholineinflammationEndotoxininterleukinBAPTAanalysis of varianceANOVAEnzyme-linked immunosorbent assayELISACytokinesHot platenerve growth factormethyllycaconitine citratepatNicotinic receptors
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Authors
B. Safieh-Garabedian, M. Oz, R. Mardam Bey, F. Shamaa, A. Ashoor, O.M. El-Agnaf, N.E. Saadé,