Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6274926 | Neuroscience | 2013 | 10 Pages |
Abstract
⺠Surgical incision enhanced the membrane translocation level of PKCγ in dorsal horns. ⺠Surgical incision induced the trafficking of GluR1 into neuronal plasmic membrane. ⺠Intrathecal PKCγ siRNA inhibited the phosphorylation of GluR1 at Serine-831 site. ⺠Intrathecal PKCγ siRNA inhibited GluR1 membrane trafficking. ⺠Intrathecal PKCγ siRNA blunted the pain hypersensitivity.
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Neuroscience
Neuroscience (General)
Authors
Y. Wang, J. Wu, R. Guo, Y. Zhao, Y. Wang, M. Zhang, Z. Chen, A. Wu, Y. Yue,