Article ID Journal Published Year Pages File Type
6274926 Neuroscience 2013 10 Pages PDF
Abstract
► Surgical incision enhanced the membrane translocation level of PKCγ in dorsal horns. ► Surgical incision induced the trafficking of GluR1 into neuronal plasmic membrane. ► Intrathecal PKCγ siRNA inhibited the phosphorylation of GluR1 at Serine-831 site. ► Intrathecal PKCγ siRNA inhibited GluR1 membrane trafficking. ► Intrathecal PKCγ siRNA blunted the pain hypersensitivity.
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Authors
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