Focal cerebral ischemia induces the neurogenic potential of mouse Dach1-expressing cells in the dorsal part of the lateral ventricles

Article ID	Journal	Published Year	Pages	File Type
6274931	Neuroscience	2013	15 Pages	PDF

Abstract

âº Identification of Dach1-expressing cells in the dorsal part of the lateral ventricles. âº They are suitable tool for studying processes of the adult neurogenesis. âº They self-renew and differentiate in vitro into glial and neuronal phenotype. âº Ischemia increases number of Dach1-expressing neuroblasts. âº These neuroblasts migrate into olfactory bulb and give rise to interneurons.

Keywords

MCA Dcx PBS TTX GCL MCAO aCSF DAPI TTC RMS EGTA bFGF interneurons GFP GFAP SVZ BLBP PLL HEPES PTB 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid 4,6-diamidino-2-phenylindole EDTA ethylene glycol tetraacetic acid Ethylenediaminetetraacetic acid middle cerebral artery occlusion phosphate buffer Lateral ventricles tetrodotoxin current densities Triphenyltetrazolium chloride tyrosine hydroxylase rostral migratory stream doublecortin adult neural stem cells middle cerebral artery basic fibroblast growth factor granular cell layer glomerular layer artificial cerebrospinal fluid Phosphate-buffered saline subventricular zone Glial fibrillary acidic protein green fluorescent protein brain lipid-binding protein Poly-l-lysine Pentobarbital Patch-clamp olfactory bulb