Expression analysis of genes involved in TLR2-related signaling pathway: Inflammation and apoptosis after ischemic brain injury

Article ID	Journal	Published Year	Pages	File Type
6274937	Neuroscience	2013	30 Pages	PDF

Abstract

âº Toll-like receptor 2 (TLR2) signaling pathway is active in mouse post ischemic brain. âº Proinflammatory response reaches its maximum 1Â week after introduced brain ischemia. âº TLR2 loss results in the decrease of proinflammatory response after brain ischemia. âº TLR2 loss results in higher expression of apoptotic factor Casp8.

Keywords

RT-PCR MCAO TLR2 inflammation middle cerebral artery occlusion Ischemia Apoptosis Brain Mouse wild type reverse transcription-polymerase chain reaction Toll-like receptor 2