| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6274983 | Neuroscience | 2013 | 9 Pages |
Abstract
⺠TBI resulted in the activation of the TAK1 signaling pathway. ⺠TAK1 inhibition decreased NF-κB and AP-1 DNA-binding activities. ⺠TAK1 inhibition down-regulated TNF-α and IL-1β production. ⺠TAK1 inhibition reduced neuronal damage. ⺠TAK1 inhibition improved the beam-walking score.
Keywords
NF-κBMMPAP-1ICVNeuNHRPDMSOElectrophoretic mobility shift assayEDTAEthylenediaminetetraacetic acidImmunofluorescenceIHCImmunohistochemistryinterleukinEnzyme-linked immunosorbent assayELISADimethylsulfoxideEMSA یا electrophoretic mobility shift assay nuclear factor-kappaBmatrix metalloproteinaseHorseradish peroxidase
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Authors
D. Zhang, Y. Hu, Q. Sun, J. Zhao, Z. Cong, H. Liu, M. Zhou, K. Li, C. Hang,