| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6275036 | Neuroscience | 2013 | 16 Pages |
Abstract
⺠5-HT2C receptor immunoreactivity was investigated in sacral spinalized rats at seven time points. ⺠After 14-day injury the 5-HT2C receptor started to upregulate in the spinal cord gray matter. ⺠5-HT2C receptor in motoneurons is significantly upregulated at 45 days after spinal cord injury. ⺠The time course of 5-HT2C receptor upregulation is positively correlated with the development of rat tail muscle spasm.
Keywords
5-HTTris-buffered saline with Triton X-100phosphate-buffered saline with Triton X-1005-HT2CRPersistent inward currentSerotonin 2C receptor5-HT2ARLLRMAP2GPCRNeuNDOIPBSPIC1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropaneBSAG-protein-coupled receptorSpinal cord injurybovine serum albuminSpasticityImmunoreactivityImmunohistochemistryLong-latency reflexSerotoninPhosphate-buffered salineneuronal nucleimicrotubule-associated protein 2ChATcholine acetyltransferaseSerotonin receptorserotonin 2A receptor
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
L.-Q. Ren, J. Wienecke, M. Chen, M. Møller, H. Hultborn, M. Zhang,