Neural expression of the transcription factor THAP1 during development in rat

Article ID	Journal	Published Year	Pages	File Type
6275125	Neuroscience	2013	14 Pages	PDF

Abstract

âº The neural expression patterns of Thap1 transcript and THAP1 protein were examined in rats. âº Thap1 transcript and THAP1 protein are expressed in the brain, spinal cord and dorsal root ganglia. âº THAP1 expression was highest in early development, particularly in the cerebellum at Postnatal Day 7. âº THAP1 immunoreactivity was detected in both the nuclear and cytoplasmic compartments of neurons.

Keywords

DYT6 PBS DRG THAP1 ROI cRNA qRT-PCR complementary RNA quantitative real-time RT-PCR Immunoreactivity THAP phosphate buffer dystonia Purkinje cells Transcription factor Phosphate-buffered saline Cerebellum region of interest ChAT choline acetyl-transferase dorsal root ganglia