Article ID Journal Published Year Pages File Type
6275143 Neuroscience 2013 12 Pages PDF
Abstract
► When given at 30 min, VPA and DZP were ineffective against pilocarpine-induced ESE. ► SPD, an amide derivative of VPA, suppressed benzodiazepine-resistant ESE. ► SPD was as efficacious as propofol and pentobarbital, even when given at 60 min. ► VCD, an SPD homolog, was also effective at 30 min.
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