| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6275146 | Neuroscience | 2013 | 12 Pages |
Abstract
⺠Transgenic tg(Prnp-SNCAâA30P)-mice develop motor deficits with age. ⺠tg(Prnp-SNCAâA30P) Tg mice have a reduced locomotor response to amphetamine. ⺠Sncatm(A30P) Tm-mice are slightly hyperactive. ⺠Neither mouse strain studied here show increased sensitivity to 6-OHDA.
Keywords
MPTPDOPAC5-HT6-OHDAPBSPFA6-Hydroxydopamine5-hydroxytryptamine1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine3,4-dihydroxyphenylacetic acidα-synucleinAsynAlpha-synucleinLewy bodiesParkinson’s diseaseanalysis of varianceANOVATransgenictargeted mutationDopamineBehaviorPhosphate-buffered salinewild-typehomovanillic acidparaformaldehydeHVA
Related Topics
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Neuroscience
Neuroscience (General)
Authors
M. Piltonen, M. Savolainen, S. Patrikainen, V. Baekelandt, T.T. Myöhänen, P.T. Männistö,