Article ID Journal Published Year Pages File Type
6275276 Neuroscience 2013 13 Pages PDF
Abstract
► Spatiotemporal upregulation of gelsolin in the brain of burned mice. ► Gelsolin was expressed in microglia/macrophage, astrocytes and neurons in the brain of burned mice. ► Gelsolin was cleaved in the brain of burned mice. ► Presence of caspase-3-positive cells and kinetic changes of caspase-3 activities in the brain of burned mice. ► Increased gelsolin expression and caspase-3-dependent cleavage of PC12 cells insulted by LPS.
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