Possible involvement of type 1 inositol 1,4,5-trisphosphate receptors up-regulated by dopamine D1 and D2 receptors in mouse nucleus accumbens neurons in the development of methamphetamine-induced place preference

Article ID	Journal	Published Year	Pages	File Type
6275300	Neuroscience	2012	8 Pages	PDF

Abstract

âº An IP3R antagonist inhibited METH-induced place preference. âº The level of IP3R-1 increased in the development of METH-induced place preference. âº Increase of IP3R-1 by METH was abolished by antagonists of D1 and D2 Rs. âº IP3R-1 plays a critical role in the development of METH-induced place preference.

Keywords

2-APB ClCr IP3Rs DMSO Ca2+-induced Ca2+ release Dimethyl sulfoxide frontal cortex