Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6275385 | Neuroscience | 2012 | 9 Pages |
Abstract
⺠We examined the effect of blocking SERCA on respiratory rhythm generation in an in vitro preparation. ⺠Thapsigargin and CPA do not affect period or amplitude of respiratory-related motor output. ⺠SERCA blockade and depletion of Ca2+ stores do not affect the mechanisms for rhythm generation. ⺠We suggest that Ca2+ from intracellular stores does not play a relevant role for rhythm generation.
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Authors
L. Beltran-Parrazal, J. Fernandez-Ruiz, R. Toledo, J. Manzo, C. Morgado-Valle,