Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6275440 | Neuroscience | 2012 | 10 Pages |
Abstract
⺠Early immune challenge in mice alters CNS stress-related gene expression. ⺠Altered gene expression occurs during a critical developmental time window. ⺠Early changes to stress-related gene expression may underlie adult behavioral dysfunction.
Keywords
5-HTPOMCCA35-HT2C5-HT2Apro-opiomelanocortinSSCdpmBLACPMmRNACA1CRHserotonin receptor 2ACrhr1LPSSerotonin receptor 2CCRHR2PBSACTHbasolateral amygdalaCeASALCentral amygdalagamma-aminobutyric acidinterleukindisintegrations per minuteneurodevelopmenttumor necrosis factor-αstandard error of the meanCNSmessenger ribonucleic acidSalinesaline-sodium citrateSerotonincentral nervous systemcounts per minutedentate gyrusTNF-αPhosphate buffered salinelipopolysaccharidePVNHPA axisSEMHPAparaventricular nucleuscorticotropin-releasing hormonehypothalamic–pituitary–adrenalPostnatalImmune challengeCORTCorticosteroneGABAMineralocorticoid receptorglucocorticoid receptor
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Authors
A. Amath, J.A. Foster, M.M. Sidor,