Breakdown in central motor control can be attenuated by motor practice and neuro-modulation of the primary motor cortex

Article ID	Journal	Published Year	Pages	File Type
6275446	Neuroscience	2012	8 Pages	PDF

Abstract

âº We measured the central and kinematic changes associated with practice and neuro-modulation. âº Motor practice of a maximal voluntary rate task was preceded by a 15-min Sham or ITMS intervention. âº Cortico-motor excitability was increased after ITMS but not Sham intervention. âº Prior ITMS attenuated movement breakdown with practice more than the Sham intervention. âº Increased cortico-motor excitability improved motor performance and learning.

Keywords

MCP MEP MVC metacarpophalangeal MVR TMS CME Spike-timing dependent plasticity Transcranial magnetic stimulation corticomotor excitability maximal voluntary contraction primary motor cortex motor-evoked potentials