Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6275479 | Neuroscience | 2012 | 10 Pages |
Abstract
⺠tPA opens the blood-brain barrier in naïve animals. ⺠NAT reduces tPA-induced changes in BBB permeability in naïve and stroke animals. ⺠tPA-NAT treatment reduces functional deficits following stroke. ⺠NAT reduces tPA-associated mortality and hemorrhage. ⺠Inhibiting neurogenic inflammation may be a novel target to treat reperfusion injury.
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Neuroscience (General)
Authors
R.J. Turner, R. Vink,