Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6275503 | Neuroscience | 2012 | 11 Pages |
Abstract
⺠Rotenone-induced behavioral deficits confirmed with SDS-PAGE and IF studies. ⺠Rotenone-induced parkinsonism elicits lower parkin and DJ1 expression. ⺠Enhanced level of caspase 3, 9, and Hsp60 in rotenone-treated PD model. ⺠Rotenone-induced neuronal damages have been seen in silver and TH staining. ⺠HSP and Ubiquitin E3 ligase can reverse the negative effect of rotenone-induced PD.
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Authors
M. Sonia Angeline, P. Chaterjee, K. Anand, R.K. Ambasta, P. Kumar,