| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6275727 | Neuroscience | 2012 | 10 Pages |
Abstract
⺠Hypoxia induces proliferation of Müller cell line rMC-1. ⺠Hypoxia skews differentiation of rMC-1 towards a retinal progenitor lineage. ⺠Blocking Notch signaling after hypoxia increased neural regeneration of rMC-1. ⺠Blocking Notch signaling after hypoxia attenuates de-differentiation of rMC-1.
Keywords
CRALBPTerminal dUTP nick end labelingTdTSox2N-methyl-d-aspartic acidNSCsFGF2PKCMsi1DAPTNMDADAPIERKGFAP4′,6-diamidino-2-phenylindole5-bromo-2′-deoxyuridineBrdUterminal deoxynucleotidyl transferaseProliferationDifferentiationTUNELMüller cellscellular retinaldehyde-binding proteinNeural stem cellsfibroblast growth factor 2Musashi-1NotchHypoxiaGlial fibrillary acidic proteinProtein kinase Cextracellular signal-regulated kinaseGlutamine synthetase
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Authors
Z. Wang, E. Sugano, H. Isago, N. Murayama, M. Tamai, H. Tomita,