| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6275836 | Neuroscience | 2012 | 16 Pages |
Abstract
â¶We examined the effect of estradiol treatment on Akt and BDNF signaling in the mouse hippocampus. â¶Estradiol treatment for 6 h increased pAkt immunoreactivity, whereas estradiol treatment for 48 h increased pTrkB immunoreactivity. â¶Estradiol effects were all blocked by knockout of estrogen receptor beta. â¶Estradiol effects on Akt and TrkB were blocked by knockout of estrogen receptor alpha.
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Authors
J.L. Spencer-Segal, M.C. Tsuda, L. Mattei, E.M. Waters, R.D. Romeo, T.A. Milner, B.S. McEwen, S. Ogawa,