| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6275909 | Neuroscience | 2012 | 9 Pages |
Abstract
â¶We investigated ADNF-9 neuroprotection in fetal alcohol exposure model. â¶ADNF-9 treatment prevented alcohol-induced reductions in fetal brain weight. â¶ADNF-9 prevented an alcohol-induced increase in cell death in fetal brain regions. â¶Neuroprotective effect of ADNF-9 is mediated through Bcl2 and JNK pathways. â¶ADNF-9 neuroprotection provides potential therapeutics in fetal alcohol exposure.
Keywords
enzyme immunometric assayADNFPBSJnkEDCHEPESFAEBcl2HRPFAS4-(2-hydroxyethyl)-1-piperazineethanesulfonic acidc-Jun N-terminal kinaseBACAlcEDTAEthylenediaminetetraacetic acidAlcoholEIATdT-mediated dUTP nick-end labelingTUNELApoptosisFetal alcohol syndromeactivity-dependent neurotrophic factorBlood alcohol concentrationFetal alcohol exposureNeuroprotectionPhosphate-buffered salineMitochondriaHorseradish peroxidase
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Authors
Y. Sari, J.M. Weedman, S. Ge,