Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6276240 | Neuroscience | 2011 | 9 Pages |
Abstract
â¶Progesterone was daily applied over 13 days starting 1 day after unilateral injection of 6-OHDA into the dorsal striatum of male rats. â¶Chronic progesterone administration increased the DOPAC/DA ratio in the lesioned striatum, increased 6-OHDA-lesion-induced motor impairments. â¶Our results raise the question of possible negative interactions between progesterone and parkinsonian symptoms in males.
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Authors
O.Y. Chao, J.P. Huston, A. von Bothmer, M.E. Pum,