Article ID Journal Published Year Pages File Type
6276240 Neuroscience 2011 9 Pages PDF
Abstract
▶Progesterone was daily applied over 13 days starting 1 day after unilateral injection of 6-OHDA into the dorsal striatum of male rats. ▶Chronic progesterone administration increased the DOPAC/DA ratio in the lesioned striatum, increased 6-OHDA-lesion-induced motor impairments. ▶Our results raise the question of possible negative interactions between progesterone and parkinsonian symptoms in males.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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