| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6276290 | Neuroscience | 2011 | 7 Pages |
Abstract
â¶Arc gene expression after novelty in FC is dependent on 5-HT2AR neurotransmission. â¶The inhibition is pharmacologically characterized. â¶The role of 5-HT2AR is site specific. No effect is observed in the hippocampus. â¶Increase in Arc mRNA and plasma corticosterone is activated via distinct mechanisms.
Keywords
MPFCACTH5-HT2AREgr-25-HT2AIEGc-fosCREBPFCLSDBDNFLysergic acid diethylamideSerotoninBrain-derived neurotrophic factorprefrontal cortexfrontal cortexmedial prefrontal cortexArcHypothalamic-pituitary-adrenal axisMouseHPANoveltyadrenocorticotropic hormonecyclic AMP response element binding proteinImmediate-early genesserotonin 2A receptor
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
M.A. Santini, A.B. Klein, M. El-Sayed, C. Ratner, G.M. Knudsen, J.D. Mikkelsen, S. Aznar,