| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6276325 | Neuroscience | 2011 | 11 Pages |
Abstract
â¶We produced the first knockout mouse of Dcdc2. â¶We find no evidence of neuronal migration disruption in the Dcdc2 mutants. â¶Dcx RNAi causes a more severe migration deficit in the Dcdc2 mutants. â¶Dcx RNAi cause a more severe effect on the growth and elaboration of dendrites in the Dcdc2 mutants. â¶Dcdc2 on its own is not required for neuronal migration in the neocortex, but does render the neocortex more susceptible to migration disruptions caused by Dcx RNAi.
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Authors
Y. Wang, X. Yin, G. Rosen, L. Gabel, S.M. Guadiana, M.R. Sarkisian, A.M. Galaburda, J.J. LoTurco,