Mechanisms underlying the protective effects of myricetin and quercetin following oxygen-glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells

▶Polypnenols reduce cell swelling following ischemia-like injury in cultures. ▶Myricetin and quercetin act differently on mitochondria. ▶Myricetin and quercetin regulate intracellular calcium. ▶Myricetin, but not quercetin, increase glutamate uptake. ▶Polyphenols have potential to reduce cytotoxic brain edema in ischemia.