| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6276545 | Neuroscience | 2011 | 6 Pages |
Abstract
â¶Increase of the endocannabinoid, 2-AG during the asymptomatic phase of prion disease. â¶Up-regulation of the expression of the CB2 receptor (mRNA and protein). â¶No alteration of the other endocannabinoid, anandamide, nor of CB1 receptor. â¶Occurrence endocannabinoid system changes concomitantly with prion formation.
Keywords
PrPcTSEPrP2-arachidonoyl-glycerol2-AGpalmitoylethanolamideoleoylethanolamideCJDPPARRT-qPCRGAPDHPEAreverse transcription-quantitative PCRCBDWPICBRAEAPrPscOEAendocannabinoidsodium dodecyl sulfate-polyacrylamide gel electrophoresisSDS-PAGEstandard deviationTransmissible spongiform encephalopathiesCreutzfeldt-Jakob diseaseNeurodegenerative diseaseBrainMousewild typepolymerase chain reactionPCRPrion proteinProteinase KPrionCannabidiolglyceraldehyde-3-phosphate dehydrogenaseperoxisome proliferator-activated receptorcannabinoid receptor
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Authors
S. Petrosino, B. Ménard, N. Zsürger, V. Di Marzo, J. Chabry,