Article ID Journal Published Year Pages File Type
6276567 Neuroscience 2011 10 Pages PDF
Abstract
▶Humanized Foxp2 enlarges dendritic trees only in the striatum, the thalamus and the neocortex. ▶Humanized Foxp2 increases synaptic plasticity in medium spiny neurons and not in Purkinje cells. ▶Humanized Foxp2 affects only a subset of the traits affected by loss-of-function Foxp2 alleles. ▶Effects of humanized Foxp2 are confined to cortico-basal-ganglia circuits.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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