Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6276591 | Neuroscience | 2011 | 12 Pages |
Abstract
â¶Neurotoxic lesions of the nucleus paragigantocellularis (nPGi) facilitated copulation, supporting the hypothesis that the nucleus paragigantocellularis, and not fibers-of-passage, provide tonic inhibitory drive to genital reflexes. â¶Neurotoxic lesions of the nPGi in females significantly decreased time spent mating with stimulus males, and attenuated the development of a conditioned place preference for sexual behavior. â¶While nPGi lesions in males facilitate copulation, such lesions in females attenuate several aspects of sexual behavior resulting in a reduction in the rewarding value of copulation that may be mediated by nPGi control of genital reflexes.
Keywords
MPOAnPGipotassium phosphate buffered salineMePDvlPAGVMNKPBSNAccN-methyl-d-aspartateSPVNeuNCPPNMDAPenisOrgasmEjaculationconditioned place preferenceSpinal trigeminal tractSex differencesVentrolateral periaqueductal graystandard error of the meanPyramidal tractPVNSEMmedial preoptic areaVaginaNucleus accumbenslateral paragigantocellular nucleusNucleus paragigantocellularisVentromedial hypothalamic nucleusparaventricular hypothalamic nucleusneuron-specific nuclear protein
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Authors
J.J. Normandin, A.Z. Murphy,