Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6278273 | Neuroscience | 2008 | 10 Pages |
Abstract
We hypothesize that the organization of A- versus C-fiber inputs to the PAG enables the coordination of coping strategies appropriate to meet the demands imposed by these different noxious stimuli. Hypothalamic-PAG projections activated by A-fiber inputs did not reflect this level of organization and we suggest that this may relate to their role in thermoregulation as opposed to autonomic responses to particular nociceptive inputs.
Keywords
LSNphosphate-buffered saline with Triton X-100DLHdl-homocysteic acidLHAPBS-TFOSFLIPAGCTBDAB3,3-diaminobenzidine tetrahydrochlorideventrolateral Fos-like immunoreactivityphosphate bufferperiaqueductal grayPainSpinal cordnociceptionlateral hypothalamic areaLateral spinal nucleusHypothalamuscholera toxin subunit B
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Authors
D.M. Parry, F.M. MacMillan, S. Koutsikou, S. McMullan, B.M. Lumb,