Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6278747 | Neuroscience | 2006 | 11 Pages |
Abstract
Taken together, these data suggest that the TREK/TRAAK K-channel family may be a promising target for neuroprotection, and that riluzole and alpha-linolenic acid could be of therapeutic value against focal ischemia/reperfusion injury to the brain.
Keywords
TRAAKTREKMCApCO2TTCALAMABPPO2MCAO2,3,5-triphenyltetrazolium chloridealpha-linolenic acidPolyunsaturated fatty acidsmiddle cerebral artery occlusionFocal ischemialong-term survivalanalysis of varianceANOVATUNELriluzolemiddle cerebral arteryPartial pressure of oxygenPartial pressure of carbon dioxidemean arterial blood pressureNeuroprotectionPalmPalmitic acid
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Authors
C. Heurteaux, C. Laigle, N. Blondeau, G. Jarretou, M. Lazdunski,