| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6279142 | Neuroscience Letters | 2016 | 4 Pages |
Abstract
A study was performed on the effects of local microinjection of melanin-concentrating hormone (MCH) into the right sublaterodorsal tegmental nucleus (SLD) on sleep and wakefulness in rats prepared for chronic sleep recordings. MCH 200Â ng significantly decreased rapid-eye-movement sleep (REMS) time during the first and second 2-h of the recording period which was related to the reduction of the number of REMS periods and the increase of REMS latency. It is proposed that REMS inhibition was related to the direct deactivation of SLD glutamatergic neurons by the peptide.
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Authors
Jaime M. Monti, Pablo Torterolo, Héctor Jantos, Patricia Lagos,