| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6279207 | Neuroscience Letters | 2016 | 7 Pages |
Abstract
In conclusion, SOCS1 overexpression in RPE cells inhibits some IFNγ-mediated responses that lead to uveitis development. This notion raises the possibility that SOCS1 overexpression could be a novel target for treating non-infectious uveitis. However, some proinflammatory effects of TNFα and IL-17 stimulation on RPE are not blocked by SOCS1 overexpression.
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Authors
Magdalena Bazewicz, Dafina Draganova, Maya Makhoul, Abdel Chtarto, Valerie Elmaleh, Liliane Tenenbaum, Laure Caspers, Catherine Bruyns, François Willermain,