Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6280825 | Neuroscience Letters | 2015 | 5 Pages |
Abstract
Although VGLUTs have been repeatedly investigated in distinct rodent epilepsy models, their expression levels were hitherto not fully unraveled in the most difficult-to-treat form of epilepsy: TLE with HS ILAE type1. We here, demonstrate for the first time that VGLUT2 protein expression is significantly decreased and VGLUT3 protein is significantly increased in the hippocampus of patients suffering from TLE with HS ILAE type1 compared to autopsy controls.
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Authors
Joeri Van Liefferinge, Cathy J. Jensen, Giulia Albertini, Eduard Bentea, Thomas Demuyser, Ellen Merckx, Eleonora Aronica, Ilse Smolders, Ann Massie,