Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6281241 | Neuroscience Letters | 2015 | 5 Pages |
Abstract
A 32-to-4% sucrose devaluation leads to suppression of consummatory behavior relative to unshifted 4% sucrose controls. This is accompanied by an emotional response inducing memory consolidation. Expression levels of phosphorylated cyclic adenosine monophosphate response element-binding protein (pCREB, a marker of synaptic plasticity) were higher after the first devaluation session than after the second in prelimbic cortex, anterior cingulate cortex, and dorso-medial striatum. The central nucleus of the amygdala showed a tendency to differential pCREB expression. This evidence contributes to identifying the brain circuit for one form of traumatic memory involving reward loss.
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Authors
Amanda C. Glueck, Torry S. Dennis, Linda I. Perrotti, Carmen Torres, Mauricio R. Papini,