Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6283071 | Neuroscience Letters | 2013 | 6 Pages |
Abstract
⺠Pharmacological inhibition of the mTOR pathway alters the hippocampal progenitor pool. ⺠Pharmacological inhibition of mTOR pathway impairs hippocampal development. ⺠Inhibition of mTOR pathway causes increased proliferation accompanied by increased apoptosis. ⺠This leads to decreased functional neurons that are important of cognition and memory.
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Neuroscience (General)
Authors
Lakshmi Raman, Xiangmei Kong, Steven G. Kernie,