Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6283110 | Neuroscience Letters | 2013 | 4 Pages |
Abstract
⺠The anti-epileptic drug, valproic acid, exhibits neuroprotective activity in an animal model of Parkinson's disease. ⺠Valproic acid attenuates dopaminergic neurodegeneration associated with human α-synuclein overproduction in C. elegans. ⺠Neuroprotection by valproic acid is mediated through ERK-MAPK signaling in vivo.
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Authors
Bwarenaba B. Kautu, Alejandro Carrasquilla, Matthew L. Hicks, Kim A. Caldwell, Guy A. Caldwell,