| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6283126 | Neuroscience Letters | 2013 | 6 Pages |
Abstract
⺠Preventive and therapeutic single administration of anti-Dll4 antibody in EAE mice. ⺠No clinical or histopathological beneficial effect of anti-Dll4 antibody treatment. ⺠Anti-Dll4 treatment decreases proliferative and Th1/Th17 immune responses.
Keywords
i.p.GM-CSFTNFPLPTh17EAECPMPHAMOGT helperp.i.PBSKlüver–BarreraDlldll4Proteolipid proteinexperimental autoimmune encephalomyelitisinterferonIFNinterleukinintraperitonealCNScentral nervous systemcounts per minutetumor necrosis factorPhosphate buffered salinedelta-like ligandgranulocyte macrophage colony-stimulating factorMultiple sclerosisNotchHematoxylin and Eosinpost-immunizationmyelin oligodendrocyte glycoprotein
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Authors
Herena Eixarch, M. José Mansilla, Carme Costa, Steve L. Kunkel, Xavier Montalban, Núria Godessart, Carmen Espejo,