Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6283516 | Neuroscience Letters | 2013 | 6 Pages |
Abstract
⺠Otospheres are generated from the cochlear epithelia of neonatal mice. ⺠Otospheres after ex vivo expansions retained the stemness characteristics. ⺠Otospheres after ex vivo expansions differentiated into hair-cell phenotypes. ⺠The activity for self-renewal in otospheres was weakened by ex vivo expansions. ⺠Otospheres after ex vivo expansions are useful for studying hair cell regeneration.
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Life Sciences
Neuroscience
Neuroscience (General)
Authors
Xiang-Xin Lou, Takayuki Nakagawa, Hiroe Ohnishi, Koji Nishimura, Juichi Ito,