Article ID Journal Published Year Pages File Type
6283562 Neuroscience Letters 2013 5 Pages PDF
Abstract
► Morphine (i.v.) produced dose-dependent inhibition of the VMR to UBD in all groups. ► U50,488H (i.v.) produced dose-dependent inhibition of the VMR in most groups. ► Bladder inflammation both EIL and as adults augmented VMRs after 1 mg/kg U50,488H. ► The same group demonstrated diminished inhibition of VMRs after 4 mg/kg U50,488H. ► A decrease in inhibition by κ-opioids could contribute to bladder pain states.
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