| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6283607 | Neuroscience Letters | 2013 | 5 Pages |
Abstract
⺠RGC survival in primary culture was examined after treatment with P2X7 antagonists and agonists. ⺠P2X7 antagonists preserved RGCs in primary culture although P2X7 agonists decreased them. ⺠P2X7 antagonists were injected into vitreous body after optic nerve crush (ONC) injuries in rats. ⺠RGCs were preserved when P2X7 antagonists were applied after ONC injury. ⺠Activation of P2X7 receptor may be involved in RGC death induced by ONC injury.
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Authors
Keigo Kakurai, Tetsuya Sugiyama, Takuji Kurimoto, Hidehiro Oku, Tsunehiko Ikeda,