Article ID Journal Published Year Pages File Type
6283652 Neuroscience Letters 2013 6 Pages PDF
Abstract
► miR-107 was down-regulated in glioma tissues and cell lines, particularly in p53-mutant U251 and A172 glioma cells. ► Transfection of wild-type p53 into glioma cells stimulate miR-107 expression. ► miR-107 inhibits cellular proliferation and arrests the cell cycle at the G0-G1 phase in glioma cells. ► miR-107 inhibits CDK6 and Notch-2 protein expression in glioma cells.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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