Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6283652 | Neuroscience Letters | 2013 | 6 Pages |
Abstract
⺠miR-107 was down-regulated in glioma tissues and cell lines, particularly in p53-mutant U251 and A172 glioma cells. ⺠Transfection of wild-type p53 into glioma cells stimulate miR-107 expression. ⺠miR-107 inhibits cellular proliferation and arrests the cell cycle at the G0-G1 phase in glioma cells. ⺠miR-107 inhibits CDK6 and Notch-2 protein expression in glioma cells.
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Authors
Lei Chen, Run Zhang, Peng Li, Yi Liu, Kun Qin, Zhi-qiang Fa, Yi-jing Liu, Yi-quan Ke, Xiao-dan Jiang,